发明授权
- 专利标题： Stabilizing and selecting recombinant DNA host cells
- 专利标题（中）： 稳定和选择重组DNA宿主细胞
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申请号： US275088申请日： 1981-06-18
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公开(公告)号： US4506013A公开(公告)日： 1985-03-19
- 发明人: Charles L. Hershberger , Anna K. Radue , Paul R. Rosteck, Jr.
- 申请人： Charles L. Hershberger , Anna K. Radue , Paul R. Rosteck, Jr.
- 申请人地址： IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： IN Indianapolis
- 主分类号： C12N1/21
- IPC分类号： C12N1/21 ; C07H21/04 ; C12N1/00 ; C12N1/06 ; C12N15/00 ; C12N15/09 ; C12N15/63 ; C12P19/34 ; C12R1/01 ; C12R1/125 ; C12R1/19 ; C12R1/38 ; C12R1/425 ; C12R1/44 ; C12R1/46 ; C12R1/465 ; C12R1/645 ; C12R1/66 ; C12R1/745 ; C12R1/80 ; C12R1/91 ; C12N1/20 ; C12P21/00 ; C12P21/02
摘要：
A method for stabilizing and selecting host cells containing recombinant DNA which expresses a functional polypeptide and the novel organisms and cloning vectors for the practice thereof. The invention further provides a simple, convenient, and inexpensive method to lyse host cells for purification of intracellular products.
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