发明授权
- 专利标题: Pyrene derivatives
- 专利标题(中): 芘衍生物
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申请号: US102275申请日: 1987-09-28
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公开(公告)号: US4820873A公开(公告)日: 1989-04-11
- 发明人: Kenneth W. Bair
- 申请人: Kenneth W. Bair
- 申请人地址: NC Research Triangle Park
- 专利权人: Burroughs Wellcome Co.
- 当前专利权人: Burroughs Wellcome Co.
- 当前专利权人地址: NC Research Triangle Park
- 优先权: GBX84105584 19840516
- 主分类号: C07D295/08
- IPC分类号: C07D295/08 ; A61K31/045 ; A61K31/135 ; A61K31/255 ; A61K31/275 ; A61K31/415 ; A61K31/42 ; A61K31/535 ; A61K31/5375 ; A61P31/00 ; A61P35/00 ; B01J27/135 ; C07B61/00 ; C07C29/147 ; C07C33/46 ; C07C63/44 ; C07C63/70 ; C07C66/02 ; C07C67/00 ; C07C69/76 ; C07C205/15 ; C07C213/00 ; C07C213/02 ; C07C215/06 ; C07C215/08 ; C07C215/10 ; C07C215/20 ; C07C215/28 ; C07C215/38 ; C07C215/42 ; C07C215/44 ; C07C217/48 ; C07C217/58 ; C07C253/00 ; C07C255/56 ; C07C255/58 ; C07C313/00 ; C07C315/04 ; C07C317/32 ; C07C317/36 ; C07C319/20 ; C07C323/32 ; C07C323/36 ; C07C323/38 ; C07D213/02 ; C07D233/61 ; C07D263/52 ; C07D263/62 ; C07D263/64 ; C07D295/10 ; C07D295/12 ; C07D295/135 ; C07D309/12 ; C07D317/32 ; C07D319/06 ; C07D498/04 ; C07D521/00 ; C07J63/00 ; C07C87/28
摘要:
The present invention relates to compounds of formula (I)ArCH.sub.2 R.sup.1 (I)or a monomethyl or a monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters thereof; acid addition salts thereof; wherein Ar is a pyrene or substituted pyrene ring system; R.sup.1 contains not more than eight carbon carbon atoms and is a group ##STR1## wherein m is 0 or 1; R.sup.5 is hydrogen;R.sup.6 and R.sup.7 are the same or different and each is hydrogen or C.sub.1-3 alkyl optionally substituted by hydroxy;R.sup.8 and R.sup.9 are the same or different and each is hydrogen or C.sub.1-3 alkyl; ##STR2## is a five- or six-membered saturated carbocyclic ring; R.sup.10 is hydrogen, methyl or hydroxymethyl;R.sup.11, R.sup.12 and R.sup.13 are the same or different and each is hydrogen or methyl;R.sup.14 is hydrogen, methyl, hydroxy, or hydroxymethyl.
公开/授权文献
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