发明授权
- 专利标题： Use of alkylenediamine derivatives for the treatment of blood flow disturbances and pharmaceutical compositions containing them
- 专利标题（中）： 使用亚烷基二胺衍生物治疗血流紊乱和含有它们的药物组合物
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申请号： US222215申请日： 1988-07-21
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公开(公告)号： US4880805A公开(公告)日： 1989-11-14
- 发明人: Erwin Bohm , Jens-Peter Holck , Wolfgang Kampe , Herbert Leinert , Bernd Muller-Beckmann , Klaus Strein
- 申请人： Erwin Bohm , Jens-Peter Holck , Wolfgang Kampe , Herbert Leinert , Bernd Muller-Beckmann , Klaus Strein
- 申请人地址： DEX Mannheim
- 专利权人： Boehringer Mannheim GmbH
- 当前专利权人： Boehringer Mannheim GmbH
- 当前专利权人地址： DEX Mannheim
- 优先权： DEX3428525 19840802
- 主分类号： C07D295/20
- IPC分类号： C07D295/20 ; A61K31/135 ; A61K31/165 ; A61K31/22 ; A61K31/33 ; A61K31/415 ; A61K31/505 ; A61K31/535 ; A61K31/5375 ; A61P7/00 ; A61P9/00 ; C07C67/00 ; C07C213/00 ; C07C217/84 ; C07C231/00 ; C07C233/25 ; C07C233/78 ; C07C235/44 ; C07C235/46 ; C07C235/50 ; C07C237/22 ; C07C237/34 ; C07C239/00 ; C07C241/00 ; C07C253/00 ; C07C255/54 ; C07C275/00 ; C07C313/00 ; C07C323/36 ; C07C323/60 ; C07D231/38 ; C07D231/56 ; C07D239/54 ; C07D521/00
摘要：
The present invention is concerned with the use of compounds of the general formula: ##STR1## wherein A is an optionally substituted phenyl or heteroaromatic radical, R.sub.6 and R.sub.7 are hydrogen or lower alkyl, X is an alkylene chain containing up to 6 carbon atoms, Y is a valency bond or a >C.dbd.O group and B is an optionally substituted phenyl or heteroaromatic radical, as well as of their pharmacologically acceptable salts for the treatment of blood flow disturbances. The present invention also provides pharmaceutical compositions which contain these compounds.