发明授权
US5114721A Preparation of T-cell and T-cell membrane for use in prevention and
treatment of autoimmune diseases
失效
T细胞和T细胞膜的制备用于预防和治疗自身免疫性疾病
- 专利标题： Preparation of T-cell and T-cell membrane for use in prevention and treatment of autoimmune diseases
- 专利标题（中）： T细胞和T细胞膜的制备用于预防和治疗自身免疫性疾病
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申请号： US323705申请日： 1989-03-15
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公开(公告)号： US5114721A公开(公告)日： 1992-05-19
- 发明人: Irun R. Cohen , Meir Shinitzky , Richard L. Edelson
- 申请人： Irun R. Cohen , Meir Shinitzky , Richard L. Edelson
- 申请人地址： ILX Rehovot
- 专利权人： Yeda Research and Development Co. Ltd.
- 当前专利权人： Yeda Research and Development Co. Ltd.
- 当前专利权人地址： ILX Rehovot
- 优先权： ILX85746 19880315
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; A61K35/14 ; A61K35/26 ; A61K39/00 ; A61P37/00
摘要：
Pharmaceutical preparations are provided for preventing or treating autoimmune diseases in which the active principle is activated T-lymphocyte cells, specific for the autoimmune disease to be treated, which cells have been treated by incubation with a photoactivatable psoralen cross-linking agent, such as 8-methoxypsoralen, and then photoactivated. The active principle may also be the membrane fraction of such cells. Such preparations may be formulated into pharmaceutical compositions and administered to prevent or treat autoimmune disesases.
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