发明授权
US5236827A Device for enhancing fluorescence and kinetics and methods of using the
device
失效
用于增强荧光和动力学的装置以及使用该装置的方法
- 专利标题: Device for enhancing fluorescence and kinetics and methods of using the device
- 专利标题(中): 用于增强荧光和动力学的装置以及使用该装置的方法
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申请号: US835009申请日: 1992-02-12
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公开(公告)号: US5236827A公开(公告)日: 1993-08-17
- 发明人: Mark L. Sussman , Stephen G. Wilson , Gregory Tice
- 申请人: Mark L. Sussman , Stephen G. Wilson , Gregory Tice
- 申请人地址: NJ Franklin Lakes
- 专利权人: Becton, Dickinson and Company
- 当前专利权人: Becton, Dickinson and Company
- 当前专利权人地址: NJ Franklin Lakes
- 主分类号: C12M1/34
- IPC分类号: C12M1/34 ; C12Q1/04 ; C12Q1/34
摘要:
A carrier having at least one kinetics and fluorescence enhancing support and a dry substance selected from the group consisting of fluorogenic substrates, B methylumbelliferone, 7-amino-4-methyl coumarin, B-napthylamine, fluoroscein, and resorufin deposited on the support demonstrates substantial enhancement of hydrolysis kinetics and fluorescence over pure liquid systems. When the device has a plurality of supports and the supports have different fluorogenic substrates an enzyme rate-of-reaction profile representative of a microorganism in the suspension can be determined and used to identify the organism. The device can also be used to characterize enzymes expressed by other biological specimens.
公开/授权文献
- US5790673A Active acoustical controlled enclosure 公开/授权日:1998-08-04
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