发明授权
- 专利标题: Isohirudins
- 专利标题(中): 异水蛭素
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申请号: US35498申请日: 1993-03-22
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公开(公告)号: US5322926A公开(公告)日: 1994-06-21
- 发明人: Dominique Tripier , Peter Crause , Paul Habermann , Martin Kramer , Joachim Engels , Matthias Scharf
- 申请人: Dominique Tripier , Peter Crause , Paul Habermann , Martin Kramer , Joachim Engels , Matthias Scharf
- 申请人地址: DEX Frankfurt am Main
- 专利权人: Hoechst Aktiengesellschaft
- 当前专利权人: Hoechst Aktiengesellschaft
- 当前专利权人地址: DEX Frankfurt am Main
- 优先权: DEX3835815 19881021
- 主分类号: A61K38/55
- IPC分类号: A61K38/55 ; A61K38/00 ; A61P7/02 ; C07K1/02 ; C07K1/113 ; C07K1/14 ; C07K1/20 ; C07K1/22 ; C07K14/81 ; C07K14/815 ; A61K37/00 ; A61K37/02 ; C07K5/00 ; C07K7/00
摘要:
Thrombin inhibitors from the hirudin family which differ from the previously known hirudins by mutation in the protein chain, and a process for their preparation are described. The novel hirudins are distinguished by a high specific activity, high stability and good pharmacokinetics.
公开/授权文献
- US5975186A Roller blinds mountings 公开/授权日:1999-11-02
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