摘要:
Thrombin inhibitors from the hirudin family which differ from the previously known hirudins by mutation in the protein chain, and a process for their preparation are described. The novel hirudins are distinguished by a high specific activity, high stability and good pharmacokinetics.
摘要:
The present invention relates to hirudin derivatives which are formed from hirudin or the physiologically acceptable salt thereof and a carrier, to a process for the preparation thereof, and to the use thereof as thrombin inhibitor.
摘要:
The invention relates to a polypeptide of the formula ##STR1## in which R represents phenoloic hydrogen or a phenolic ester group and m, n, X, Z, A, B, C, D, E, F, G, I and J have the meanings given, and in which the 6 Cys radicals are linked in pairs via disulfide bridges, processes for the preparation or isolation thereof, their use and agents containing them.
摘要:
A method is disclosed for assigning measurement data of a body of a patient to information data related to the same body. The method includes providing annotated measurement data, providing annotated information data, translating the first group of annotations into a first group of universal annotations and the second group of annotations into a second group of universal medical annotations in a universal annotation ontology management system, comparing the universal annotations of the first group of universal annotations with the universal annotations of the second group of universal annotations, and assigning the universal annotations to each other. An assignment system and a universal annotation ontology management system are also disclosed.
摘要:
A safety device for the protection of pedestrians involved in a collision with a vehicle is arranged in the zone of the front hood of the vehicle. The safety device is in the form of a mechanism for raising the rear of the front hood, which mechanism can be triggered by a sensor installation arranged in the zone of the front bumper of the vehicle for detection of a collision with the pedestrian. Upon detection of a collision, the mechanism raises the front hood from a rest position to an impact position in which the potential for contact between the pedestrian's head and the windshield are reduced.
摘要:
In order to compare high-dimensional, multi-modal data for a patient to data for other patients, deep learning is used to encode original, multi-modal data for a patient into a compact signature. The compact signature is compared to predetermined compact signatures generated for other patients, and similar predetermined compact signatures are identified based on the comparison. A clinical outcome may be predicted based on the similar predetermined compact signatures that are identified.
摘要:
Methods and device are disclosed for data retrieval. At first images and reports are analyzed by respective parser units to detect both structures and text passages that are related to respective structures and text passages of a knowledge data-base. The detected structures and text passages are stored together with a unique resource located that identifies the respective structure and/or text passage at the knowledge database in a semantic annotation database. In addition a feature extraction can be performed to provide specific features of the images and/or regions of the images, whereby the features are stored in an image feature database. Finally an input query can ask questions that are used to provide a result to the query based on the semantic annotation database and the image feature database. The methods and devices may be used for data preparation and data retrieval of medical images and associated medical reports.
摘要:
A magnetic field measuring system is disclosed. The magnetic field measuring system includes a substrate, a conductive well formed in the substrate, the well having a first side with a first length, a first contact electrically coupled to the conductive well at a first location of the first side, a second contact electrically coupled to the conductive well at a second location of the first side, wherein the distance between the first location and the second location is less than the first length, a stimulus circuit coupled to the first contact and the second contact, and a sensor for identifying a property indicative of the length of a current path from the first location to the second location through the conductive well.
摘要:
Methods and device are disclosed for data retrieval. At first images and reports are analyzed by respective parser units to detect both structures and text passages that are related to respective structures and text passages of a knowledge data-base. The detected structures and text passages are stored together with a unique resource located that identifies the respective structure and/or text passage at the knowledge database in a semantic annotation database. In addition a feature extraction can be performed to provide specific features of the images and/or regions of the images, whereby the features are stored in an image feature database. Finally an input query can ask questions that are used to provide a result to the query based on the semantic annotation database and the image feature database. The methods and devices may be used for data preparation and data retrieval of medical images and associated medical reports.
摘要:
The present invention relates to a process for producing a wear-resistant coating and to a wear-resistant coating on predetermined surfaces (2) of machine or engine parts (1) consisting of a sintered material which are exposed to frictional wear, for fuel feed units in particular, comprising at least one metal-free amorphous hydrocarbon layer (5) with sp2- and sp3-hybridized carbon applied to the predetermined surface (2) of the machine or engine part (1) for reducing friction and increasing the wear resistance of the predetermined surface (2) of the machine or engine part (1).