发明授权
- 专利标题: Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
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申请号: US38766申请日: 1993-03-24
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公开(公告)号: US5489508A公开(公告)日: 1996-02-06
- 发明人: Michael D. West , Jerry Shay , Woodring Wright
- 申请人: Michael D. West , Jerry Shay , Woodring Wright
- 申请人地址: TX Austin
- 专利权人: University of Texas System Board of Regents
- 当前专利权人: University of Texas System Board of Regents
- 当前专利权人地址: TX Austin
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K31/70 ; A61K31/7088 ; A61K31/7105 ; A61K38/00 ; A61K38/43 ; A61K38/45 ; A61K38/55 ; A61K45/00 ; A61K48/00 ; A61K49/00 ; A61P35/00 ; A61P43/00 ; C12N5/00 ; C12N5/16 ; C12N9/12 ; C12N15/10 ; C12N15/113 ; C12Q1/25 ; C12Q1/48 ; C12Q1/68 ; C12Q1/70 ; G01N33/573 ; C12P19/34 ; C07H21/04
摘要:
Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to inhibit telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity.
公开/授权文献
- USPP11254P Chrysanthemum plant named `Ibis` 公开/授权日:2000-02-29
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