- 专利标题： Total synthesis of taxol
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申请号： US350251申请日： 1994-12-05
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公开(公告)号： US5527924A公开(公告)日： 1996-06-18
- 发明人: Samuel J. Danishefsky , William G. Bornmann , Yves Queneau , Thomas V. Magee , Walter J. Krol
- 申请人： Samuel J. Danishefsky , William G. Bornmann , Yves Queneau , Thomas V. Magee , Walter J. Krol
- 申请人地址： NY New York
- 专利权人： Sloan-Kettering Institute for Cancer Research
- 当前专利权人： Sloan-Kettering Institute for Cancer Research
- 当前专利权人地址： NY New York
- 主分类号： A61K31/335
- IPC分类号： A61K31/335 ; C07C13/28 ; C07C45/29 ; C07C45/59 ; C07C49/603 ; C07C49/613 ; C07C49/687 ; C07C49/713 ; C07C49/723 ; C07C49/737 ; C07C49/747 ; C07C49/753 ; C07C49/757 ; C07C255/31 ; C07C255/45 ; C07C255/46 ; C07D305/14 ; C07D317/72 ; C07D339/08 ; C07D493/04 ; C07F7/18 ; C07D317/12
摘要：
The present invention provides two basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as well as analogs to taxol. Both the intermediates and analogs to taxol may prove to be valuable anticancer agents.
公开/授权文献
- USPP7302P Lily plant named Italia 公开/授权日：1990-08-21
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