发明授权
- 专利标题： Immunogenic compositions against gastrin peptides
- 专利标题（中）： 针对胃泌素肽的免疫原性组合物
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申请号： US721638申请日： 1991-07-22
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公开(公告)号： US5607676A公开(公告)日： 1997-03-04
- 发明人: Philip C. Gevas , Stephen L. Karr , Stephen Grimes , Richard L. Littenberg
- 申请人： Philip C. Gevas , Stephen L. Karr , Stephen Grimes , Richard L. Littenberg
- 申请人地址： CA Woodland
- 专利权人： Aphton Corporation
- 当前专利权人： Aphton Corporation
- 当前专利权人地址： CA Woodland
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K38/00 ; A61K38/22 ; A61K39/00 ; A61K39/395 ; A61P1/04 ; C07K5/113 ; C07K7/06 ; C07K7/08 ; C07K14/00 ; C07K14/575 ; C07K14/595 ; C07K16/00 ; C07K16/26 ; C07K19/00 ; C07K5/00 ; A61K39/385
摘要：
Immunogenic compositions useful for the treatment of ulcers or tumors whose growth is dependent on or stimulated by gastrin hormones are disclosed. The immunogenic compositions induce antibodies in a subject which selectively neutralize the specific hormones. Pharmaceutical compositions comprising effective amounts of the immunogenic compositions and methods of treatment using the compositions are disclosed. A method of reversing the inventive treatments by neutralizing the antibodies induced in vivo is also disclosed.