发明授权
- 专利标题: Compounds having effects on serotonin-related systems
- 专利标题(中): 对5-羟色胺相关系统有影响的化合物
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申请号: US468948申请日: 1995-06-06
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公开(公告)号: US5627196A公开(公告)日: 1997-05-06
- 发明人: James E. Audia , David J. Hibschman , Joseph H. Krushinski, Jr. , Thomas E. Mabry , Jeffrey S. Nissen , Kurt Rasmussen , Vincent P. Rocco , John M. Schaus , Dennis C. Thompson , David T. Wong
- 申请人: James E. Audia , David J. Hibschman , Joseph H. Krushinski, Jr. , Thomas E. Mabry , Jeffrey S. Nissen , Kurt Rasmussen , Vincent P. Rocco , John M. Schaus , Dennis C. Thompson , David T. Wong
- 申请人地址: IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: IN Indianapolis
- 主分类号: C07D209/08
- IPC分类号: C07D209/08 ; C07D401/10 ; C07D401/12 ; C07D401/14 ; C07D403/10 ; C07D403/12 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07D413/12 ; C07D471/08 ; C07D471/10 ; C07D491/10 ; C07D491/20 ; C07D495/10 ; C07D513/04 ; A61K31/445 ; C07D409/00
摘要:
A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1.sub.A receptor. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
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