发明授权
US5719169A Substituted benzoylguanidines, their use as a medicament or diagnostic,
and medicament containing them
失效
取代的苯甲酰胍,它们作为药物或诊断物的用途,以及含有它们的药物
- 专利标题: Substituted benzoylguanidines, their use as a medicament or diagnostic, and medicament containing them
- 专利标题(中): 取代的苯甲酰胍,它们作为药物或诊断物的用途,以及含有它们的药物
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申请号: US674991申请日: 1996-07-03
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公开(公告)号: US5719169A公开(公告)日: 1998-02-17
- 发明人: Heinz-Werner Kleemann , Hans-Jochen Lang , Jan-Robert Schwark , Andreas Weichert , Wolfgang Scholz , Udo Albus
- 申请人: Heinz-Werner Kleemann , Hans-Jochen Lang , Jan-Robert Schwark , Andreas Weichert , Wolfgang Scholz , Udo Albus
- 申请人地址: DEX Frankfurt am Main
- 专利权人: Hoechst Aktiengesellschaft
- 当前专利权人: Hoechst Aktiengesellschaft
- 当前专利权人地址: DEX Frankfurt am Main
- 优先权: DEX4325822.0 19930731
- 主分类号: C07D233/64
- IPC分类号: C07D233/64 ; A01N1/02 ; A61K31/40 ; A61K31/41 ; A61K31/415 ; A61K31/44 ; A61K31/4402 ; A61K31/4406 ; A61K31/4409 ; A61K31/4418 ; A61P1/16 ; A61P3/10 ; A61P9/00 ; A61P9/06 ; A61P9/08 ; A61P9/10 ; A61P11/00 ; A61P13/02 ; A61P13/08 ; A61P13/12 ; A61P15/00 ; A61P25/28 ; A61P35/00 ; A61P43/00 ; C07C279/22 ; C07D207/333 ; C07D207/337 ; C07D213/30 ; C07D231/12 ; C07D233/54 ; C07D233/58 ; C07D521/00 ; C07D213/02
摘要:
The invention relates to benzoylguanidines of the formula I: ##STR1## to pharmaceutically acceptable salts of these compounds and to a process for preparing compounds of the formula I, which comprise reacting a compound of the formula II ##STR2## with guanidine. The compounds of the invention are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for the prophylaxis and treatment of infarction and for the treatment of angina pectoris.
公开/授权文献
- USD288782S Combined bottle and stopper therefor 公开/授权日:1987-03-17
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