- 专利标题： Glycoprotein IIb/IIIa antagonists
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申请号： US376191申请日： 1995-01-19
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公开(公告)号： US5731324A公开(公告)日： 1998-03-24
- 发明人: Matthew J. Fisher , Anne Marie Happ , Joseph A. Jakubowski , Michael Dean Kinnick , Allen D. Kline , Michael John Martinelli , John Michael Morin, Jr. , Michael Paal , Gerd Ruhter , Kenneth James Ruterbories , Daniel J. Sall , Theo Schotten , Marshall A. Skelton , Wolfgang Stenzel , Robert Theodore Vasileff
- 申请人： Matthew J. Fisher , Anne Marie Happ , Joseph A. Jakubowski , Michael Dean Kinnick , Allen D. Kline , Michael John Martinelli , John Michael Morin, Jr. , Michael Paal , Gerd Ruhter , Kenneth James Ruterbories , Daniel J. Sall , Theo Schotten , Marshall A. Skelton , Wolfgang Stenzel , Robert Theodore Vasileff
- 申请人地址： IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： IN Indianapolis
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/195 ; A61K31/215 ; A61K31/335 ; A61K31/35 ; A61K31/352 ; A61K31/38 ; A61K31/381 ; A61K31/44 ; A61K31/4427 ; A61K31/443 ; A61K31/445 ; A61K31/4465 ; A61K31/47 ; A61K31/472 ; A61K31/495 ; A61P7/02 ; A61P9/10 ; C07C257/18 ; C07C257/20 ; C07C271/64 ; C07D211/22 ; C07D211/32 ; C07D211/34 ; C07D213/82 ; C07D217/04 ; C07D217/06 ; C07D217/24 ; C07D221/00 ; C07D311/22 ; C07D311/58 ; C07D311/66 ; C07D311/70 ; C07D319/16 ; C07D333/38 ; C07D401/12 ; C07D405/06 ; C07D405/12 ; C07D491/052 ; C07D497/04 ; G03F7/20 ; C07D311/02
摘要：
This invention relates to certain bicyclic compounds having a nucleus formed of two fused six membered rings, for example, benzopyran, isoquinoline, isoquinolone, tetrahydronaphthalene, dihydronaphthalene, or tetralone, substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.
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