发明授权
- 专利标题: Methods and apparatus for synthesizing labeled combinatorial chemistrylibraries
- 专利标题(中): 合成标记组合化学品的方法和装置
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申请号: US480438申请日: 1995-06-07
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公开(公告)号: US5770455A公开(公告)日: 1998-06-23
- 发明人: John Cargill , Robert W. Armstrong
- 申请人: John Cargill , Robert W. Armstrong
- 申请人地址: CA Carlsbad
- 专利权人: Ontogen Corporation
- 当前专利权人: Ontogen Corporation
- 当前专利权人地址: CA Carlsbad
- 主分类号: C07D203/12
- IPC分类号: C07D203/12 ; A61K31/215 ; A61K38/00 ; A61P25/02 ; A61P35/00 ; B01J19/00 ; C07B43/06 ; C07B61/00 ; C07C279/02 ; C07D205/08 ; C07D233/72 ; C07D303/46 ; C07D405/12 ; C07H21/00 ; C07K1/04 ; C07K5/103 ; C07K5/117 ; C07K7/06 ; C08B37/00 ; C08F8/30 ; C40B40/06 ; C40B40/10 ; C40B40/12 ; C40B60/14 ; C40B70/00 ; G01N33/53 ; G01N33/532 ; G01N33/543 ; G01N33/552 ; G01N33/553 ; G01N33/544
摘要:
The present invention provides labeled synthetic libraries of random oligomers and methods and apparatus for generating labeled synthetic oligomer libraries. Each member of such a library is labeled with a unique identifier tag that specifies the structure or sequence of the oligomer. In a preferred embodiment of the present invention the identifier tag is a microchip that is pre-encoded or encodable with information that is related back to a detector when the identifier tag is pulsed with electromagnetic radiation.
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