发明授权
- 专利标题： Human phosphorylase kinase gamma subunit
- 专利标题（中）： 人类磷酸化酶激酶γ亚基
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申请号： US919627申请日： 1997-08-28
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公开(公告)号： US5833981A公开(公告)日： 1998-11-10
- 发明人: Olga Bandman , Surya K. Goli
- 申请人： Olga Bandman , Surya K. Goli
- 申请人地址： CA Palo Alto
- 专利权人： Incyte Pharmaceuticals, Inc.
- 当前专利权人： Incyte Pharmaceuticals, Inc.
- 当前专利权人地址： CA Palo Alto
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; A61K38/48 ; A61K48/00 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N9/12 ; C12N15/54 ; C12R1/19 ; A61K38/51 ; C12N1/20 ; C12N15/00
摘要：
The present invention provides a novel human phosphorylase kinase gamma subunit (HPHKG) and the polynucleotide which identifies and encodes HPHKG. The invention provides for expression vectors and host cells comprising the nucleic acid sequence encoding HPHKG. The invention also provides pharmaceutical compositions containing purified HPHKG or antisense molecules to HPHKG for the treatment of diseases associated with expression of HPHKG. The invention also includes diagnostic compositions containing the polynucleotide, fragments or the complement thereof, which hybridize with the genomic sequence or the transcript of polynucleotides encoding HPHKG or anti-HPHKG antibodies which specifically bind to HPHKG, and the use of such compositions for diagnosis of disease.
公开/授权文献
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