- 专利标题： 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents
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申请号： US319820申请日： 1994-10-12
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公开(公告)号： US5840751A公开(公告)日： 1998-11-24
- 发明人: Edmund Lee Ellsworth , Elizabeth Lunney , Bradley Dean Tait
- 申请人： Edmund Lee Ellsworth , Elizabeth Lunney , Bradley Dean Tait
- 申请人地址： NJ Morris Plains
- 专利权人： Warner-Lambert Company
- 当前专利权人： Warner-Lambert Company
- 当前专利权人地址： NJ Morris Plains
- 主分类号： C07C321/26
- IPC分类号： C07C321/26 ; C07C323/20 ; C07C323/22 ; C07D211/86 ; C07D309/32 ; C07D311/96 ; C07D405/04 ; C07D405/12 ; C07D407/06 ; C07D407/12 ; A61K31/35 ; A61K31/415 ; A61K31/44 ; A61K31/505
摘要：
The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized 5,6-dihydropyrones and of related structures.
公开/授权文献
- US4937459A Alignment signal detecting device 公开/授权日：1990-06-26
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