发明授权
- 专利标题: HIV immunogenic complexes
- 专利标题(中): HIV免疫复合物
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申请号: US464680申请日: 1995-12-20
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公开(公告)号: US5843454A公开(公告)日: 1998-12-01
- 发明人: Anthony L. Devico , Ranajit Pal , Mangalasseril G. Sarngadharan
- 申请人: Anthony L. Devico , Ranajit Pal , Mangalasseril G. Sarngadharan
- 申请人地址: NLX Arnhem
- 专利权人: Akzo Nobel N.V.
- 当前专利权人: Akzo Nobel N.V.
- 当前专利权人地址: NLX Arnhem
- 主分类号: G01N33/569
- IPC分类号: G01N33/569 ; A01N65/00 ; A61K39/00 ; A61K39/21 ; A61K39/385 ; A61K39/395 ; A61P31/12 ; A61P31/18 ; C07K14/16 ; C07K14/42 ; C07K14/73 ; C07K16/00 ; C07K16/10 ; C07K16/28 ; C07K19/00 ; C12N5/06 ; C12N5/10 ; C12N5/20 ; C12N15/02 ; C12P21/08 ; C12Q1/70 ; G01N33/53 ; G01N33/577
摘要:
A vaccine and a method of raising neutralizing antibodies against HIV infection. The vaccine comprises a complex of gp120 covalently bonded to CD4 or to succinyl concanvalin A. Also disclosed are immunological tests using the complex or antibody thereto for detection of HIV infection.