发明授权
- 专利标题: Complementary adenoviral systems and cell lines
- 专利标题(中): 互补腺病毒系统和细胞系
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申请号: US572126申请日: 1995-12-14
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公开(公告)号: US5851806A公开(公告)日: 1998-12-22
- 发明人: Imre Kovesdi , Douglas E. Brough , Duncan L. McVey , Joseph T. Bruder , Alena Lizonova
- 申请人: Imre Kovesdi , Douglas E. Brough , Duncan L. McVey , Joseph T. Bruder , Alena Lizonova
- 申请人地址: MD Rockville
- 专利权人: GenVec, Inc.
- 当前专利权人: GenVec, Inc.
- 当前专利权人地址: MD Rockville
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K31/70 ; A61K35/76 ; A61K38/00 ; A61K39/00 ; A61K48/00 ; A61P37/04 ; A61P43/00 ; C07K14/075 ; C07K14/47 ; C12N5/10 ; C12N7/00 ; C12N15/00 ; C12N15/12 ; C12N15/34 ; C12N15/86 ; C12N15/861 ; C12Q1/02 ; C12Q1/68 ; C12R1/92 ; G01N33/15 ; C12P19/34 ; C12N15/11 ; C12N5/16 ; C12N5/22
摘要:
The present invention provides multiply replication deficient adenoviral vectors having a spacer in at least one replication deficient adenoviral region, as well as complementing cell lines therefor. Also provided are means of constructing the multiply replication deficient adenoviral vectors and methods of use thereof, e.g., in gene therapy.
公开/授权文献
- US4521491A Flame-retarded copper-clad laminate 公开/授权日:1985-06-04
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