- 专利标题: Base-modified enzymatic nucleic acid
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申请号: US435398申请日: 1995-05-05
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公开(公告)号: US5879938A公开(公告)日: 1999-03-09
- 发明人: Nassim Usman , Leonid Beigelman , James McSwiggen , Alex Karpeisky
- 申请人: Nassim Usman , Leonid Beigelman , James McSwiggen , Alex Karpeisky
- 申请人地址: CO Boulder
- 专利权人: Ribozyme Pharmaceuticals, Inc.
- 当前专利权人: Ribozyme Pharmaceuticals, Inc.
- 当前专利权人地址: CO Boulder
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07H19/06 ; C07H19/10 ; C07H19/16 ; C07H19/20 ; C07H21/00 ; C07K14/08 ; C12N15/113 ; C12N15/85 ; C12N15/86 ; C12Q1/70 ; C07H21/04 ; C12N15/00
摘要:
Method to produce a more active ribozyme by introducing a modified base into a substrate binding arm of the ribozyme or its catalytic core.
公开/授权文献
- US4946749A Coated near-alpha titanium articles 公开/授权日:1990-08-07
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