发明授权
- 专利标题： 2'-modified oligonucleotides
- 专利标题（中）： 2'-修饰的寡核苷酸
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申请号： US35357申请日： 1998-03-05
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公开(公告)号： US06005087A公开(公告)日： 1999-12-21
- 发明人: Phillip Dan Cook , Andrew Mamoru Kawasaki
- 申请人： Phillip Dan Cook , Andrew Mamoru Kawasaki
- 申请人地址： CA Carlsbad
- 专利权人： ISIS Pharmaceuticals, Inc.
- 当前专利权人： ISIS Pharmaceuticals, Inc.
- 当前专利权人地址： CA Carlsbad
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K48/00 ; C07H19/04 ; C07H19/06 ; C07H19/10 ; C07H19/16 ; C07H19/20 ; C07H21/00 ; C07H21/04 ; C07H23/00 ; C07J43/00 ; C12N9/02 ; C12N15/113 ; C12Q1/68
摘要：
Compositions and methods are provided for the treatment and diagnosis of diseases amenable to modulation of the production of selected proteins. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the 2'-deoxyfuranosyl moieties of the nucleoside unit is modified. Treatment of diseases caused by various viruses and other causative agents is provided.
公开/授权文献
- USD378976S Glass canister with lid 公开/授权日：1997-04-29
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