发明授权
US6017536A Simian immunodeficiency virus peptides with antifusogenic and antiviral
activities
失效
具有抗融合和抗病毒活性的猿猴免疫缺陷病毒肽
- 专利标题: Simian immunodeficiency virus peptides with antifusogenic and antiviral activities
- 专利标题(中): 具有抗融合和抗病毒活性的猿猴免疫缺陷病毒肽
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申请号: US360107申请日: 1994-12-20
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公开(公告)号: US6017536A公开(公告)日: 2000-01-25
- 发明人: Shawn O'Lin Barney , Dennis Michael Lambert , Stephen Robert Petteway , Alphonse J. Langlois
- 申请人: Shawn O'Lin Barney , Dennis Michael Lambert , Stephen Robert Petteway , Alphonse J. Langlois
- 申请人地址: NC Durham
- 专利权人: Trimeris, Inc.
- 当前专利权人: Trimeris, Inc.
- 当前专利权人地址: NC Durham
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K39/00 ; A61P31/18 ; C07K5/083 ; C07K5/087 ; C07K5/09 ; C07K5/093 ; C07K5/103 ; C07K5/107 ; C07K5/113 ; C07K5/117 ; C07K14/02 ; C07K14/05 ; C07K14/11 ; C07K14/115 ; C07K14/12 ; C07K14/125 ; C07K14/13 ; C07K14/135 ; C07K14/15 ; C07K14/155 ; C07K14/16 ; C07K14/21 ; C07K14/22 ; C07K14/285 ; C07K14/31 ; A61K39/21
摘要:
The present invention relates to peptides which exhibit antifusogenic and antiviral activities. The peptides of the invention consist of a 16 to 39 amino acid region of a simian immunodeficiency virus (SIV) protein. These regions were identified through computer algorithms capable of recognizing the ALLMOTI5, 107.times.178.times.4, or PLZIP amino acid motifs. These motifs are associated with the antifusogenic and antiviral activities of the claimed peptides.
公开/授权文献
- US4996422A Mass spectrometer 公开/授权日:1991-02-26
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