发明授权
US6051419A Genes which influence pichia proteolytic activity, and uses therefor
失效
影响毕赤酵母蛋白水解活性的基因及其用途
- 专利标题： Genes which influence pichia proteolytic activity, and uses therefor
- 专利标题（中）： 影响毕赤酵母蛋白水解活性的基因及其用途
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申请号： US787806申请日： 1997-01-22
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公开(公告)号： US6051419A公开(公告)日： 2000-04-18
- 发明人: Martin A. Gleeson , Bradley D. Howard
- 申请人： Martin A. Gleeson , Bradley D. Howard
- 申请人地址： CA LaJolla
- 专利权人： SIBIA Neurosciences, Inc.
- 当前专利权人： SIBIA Neurosciences, Inc.
- 当前专利权人地址： CA LaJolla
- 主分类号： C09K13/00
- IPC分类号： C09K13/00 ; C07K14/39 ; C07K14/65 ; C12N1/19 ; C12N9/48 ; C12N9/60 ; C12N9/88 ; C12N15/09 ; C12N15/57 ; C12N15/81 ; C12R1/84 ; C12N1/14 ; C07H21/04 ; C12N1/00 ; C12N15/00
摘要：
The isolation and characterization of genes involved in proteolytic processing in species of the genus Pichia is described. The availability of such genes has enabled the generation of strains of Pichia which are deficient in proteolytic activity, which strains are useful as hosts for the expression of proteolytically sensitive recombinant products. The isolation and characterization of additional genes from species of the genus Pichia is also described, as well as uses therefore.
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