发明授权
- 专利标题： Ubiquitin conjugating enzymes
- 专利标题（中）： 泛素缀合酶
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申请号： US767942申请日： 1996-12-17
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公开(公告)号： US06068982A公开(公告)日： 2000-05-30
- 发明人: Mark Rolfe , Maria Isabel Chiu , Guillaume Cottarel , Vivian Berlin , Veronique Damagnez , Giulio Draetta
- 申请人： Mark Rolfe , Maria Isabel Chiu , Guillaume Cottarel , Vivian Berlin , Veronique Damagnez , Giulio Draetta
- 申请人地址： MA Cambridge
- 专利权人： Mitotix, Inc.
- 当前专利权人： Mitotix, Inc.
- 当前专利权人地址： MA Cambridge
- 主分类号： G01N33/48
- IPC分类号： G01N33/48 ; C07K16/40 ; C12N9/00 ; C12N15/00 ; C12N15/09 ; C12Q1/25 ; C12Q1/68 ; C12R1/91 ; G01N33/53 ; G01N33/68
摘要：
The present invention relates to drug screening assays which provide a systematic and practical approach for the identification of candidate agents able to inhibit ubiquitin-mediated degradation of a cell-cycle regulatory protein, such as p53, p27, myc, fos, MAT.alpha.2, or cyclins. The invention further relates to novel ubiquitin-conjugating enzymes, and uses related thereto.
公开/授权文献
- US4138928A Fluid actuated apparatus 公开/授权日：1979-02-13