Invention Grant
US6083523A Implantable biocompatable immunoisolatory vehicle for delivery of
selected therapeutic products
有权
用于递送选定治疗产品的可植入生物相容性免疫佐剂
- Patent Title: Implantable biocompatable immunoisolatory vehicle for delivery of selected therapeutic products
- Patent Title (中): 用于递送选定治疗产品的可植入生物相容性免疫佐剂
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Application No.: US148671Application Date: 1998-09-04
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Publication No.: US6083523APublication Date: 2000-07-04
- Inventor: Keith E. Dionne , Dwaine F. Emerich , Diane Hoffman , Paul R. Sanberg , Lisa Christenson , Orion D. Hegre , David W. Scharp , Paul E. Lacy , Patrick Aebischer , Alfred V. Vasconcellos , Michael J. Lysaght , Frank T. Gentile
- Applicant: Keith E. Dionne , Dwaine F. Emerich , Diane Hoffman , Paul R. Sanberg , Lisa Christenson , Orion D. Hegre , David W. Scharp , Paul E. Lacy , Patrick Aebischer , Alfred V. Vasconcellos , Michael J. Lysaght , Frank T. Gentile
- Applicant Address: RI Providence RI Providence
- Assignee: Brown University Research Foundation,Brown University
- Current Assignee: Brown University Research Foundation,Brown University
- Current Assignee Address: RI Providence RI Providence
- Main IPC: A61F2/02
- IPC: A61F2/02 ; A61K9/00 ; A61K9/48 ; A61K9/50 ; A61K35/12 ; A61K35/30 ; A61K35/39 ; A61K38/18 ; A61K39/395 ; A61K47/36 ; A61K48/00 ; A61L27/00 ; C12N5/00 ; C12N5/071 ; C12N5/077
Abstract:
An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region containing isolated cells and materials sufficient to maintain the cells, and a permselective, biocompatible, peripheral region free of the isolated cells, which immunoisolates the core yet provides for the delivery of the secreted product or metabolic function to the individual.
Public/Granted literature
- US4939506A Grounding brush monitor Public/Granted day:1990-07-03
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