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US6133046A Microsystems for biological analyses, their use for detecting analytes, and method for producing them 失效
用于生物分析的微系统,其用于检测分析物的用途及其生产方法

Microsystems for biological analyses, their use for detecting analytes,
and method for producing them
Abstract:
An apparatus for detecting an analyte in a sample, including a cell with at least one fixed electrode, at least one mobile electrode opposite the fixed electrode, the mobile electrode being configured to move with respect to the fixed electrode, and a sample receiving cavity defined by a space between the fixed electrode and the mobile electrode, wherein a surface of at least one of the fixed electrode and mobile electrode facing the sample receiving cavity is configured to bound a ligand of the analyte to be detected. The apparatus also includes a displacement mechanism configured to move the mobile electrode; and an external circuit connected to the fixed electrode and to the mobile electrode, and configured to measure a parameter having a value depending on the presence between the fixed electrode and the mobile electrode of the analyte to be detected.
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