发明授权
US06670482B2 Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes
有权
制备异恶唑啉-3-基酰基苯的方法和新型中间体
- 专利标题: Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes
- 专利标题(中): 制备异恶唑啉-3-基酰基苯的方法和新型中间体
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申请号: US10223019申请日: 2002-08-19
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公开(公告)号: US06670482B2公开(公告)日: 2003-12-30
- 发明人: Wolfgang von Deyn , Joachim Gebhardt , Michael Rack , Rene Lochtman , Norbert Götz , Michael Keil , Matthias Witschel , Helmut Hagen , Ulf Misslitz , Ernst Baumann
- 申请人: Wolfgang von Deyn , Joachim Gebhardt , Michael Rack , Rene Lochtman , Norbert Götz , Michael Keil , Matthias Witschel , Helmut Hagen , Ulf Misslitz , Ernst Baumann
- 优先权: DE19852095 19981112; EP03006 19990504
- 主分类号: C07D26104
- IPC分类号: C07D26104
摘要:
The present invention describes a process for preparing isoxazoles of the formula I where: R1 is hydrogen, C1-C6-alkyl, R2 is hydrogen, C1-C6-alkyl, R3, R4, R5 are each hydrogen, C1-C6-alkyl or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are each as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Furthermore, the invention describes novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates.
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