发明授权
US06921767B2 Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
失效
环烷基链烷酸作为整联蛋白受体拮抗剂衍生物
- 专利标题： Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
- 专利标题（中）： 环烷基链烷酸作为整联蛋白受体拮抗剂衍生物
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申请号： US10326299申请日： 2002-12-20
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公开(公告)号： US06921767B2公开(公告)日： 2005-07-26
- 发明人: Nagarajan R. Srinivasan , Ish Kumar Khanna , Michael Clare , Alan Gasiecki , Thomas Rogers , Barbara Chen , Mark Russell , Hwang-Fun Lu , Yu Yi , Renee M. Huff , Bipinchandra N. Desai , Balekudru Devadas , Mihir D. Parikh , Thomas Penning
- 申请人： Nagarajan R. Srinivasan , Ish Kumar Khanna , Michael Clare , Alan Gasiecki , Thomas Rogers , Barbara Chen , Mark Russell , Hwang-Fun Lu , Yu Yi , Renee M. Huff , Bipinchandra N. Desai , Balekudru Devadas , Mihir D. Parikh , Thomas Penning
- 申请人地址： US MO Chesterfield
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： US MO Chesterfield
- 代理机构： Harness, Dickey & Pierce, P.L.C.
- 主分类号： C07D213/74
- IPC分类号： C07D213/74 ; C07D231/38 ; C07D233/88 ; C07D405/12 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; C07D498/04 ; C07D239/14 ; A61K31/505 ; A61P9/10 ; A61P19/10
摘要：
The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the αvβ3 and/or αvβ5 integrin.