- 专利标题： Compositions and methods for the therapy and diagnosis of prostate cancer
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申请号： US10012896申请日： 2001-12-10
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公开(公告)号： US06943236B2公开(公告)日： 2005-09-13
- 发明人: Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , Robert A. Henderson , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher
- 申请人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler , Robert A. Henderson , John Hural , Patricia D. McNeill , Raymond L. Houghton , Carlota Vinals y de Bassols , Teresa M. Foy , Yoshihiro Watanabe , Madeleine Joy Meagher
- 申请人地址： US WA Seattle
- 专利权人： Corixa Corporation
- 当前专利权人： Corixa Corporation
- 当前专利权人地址： US WA Seattle
- 代理机构： SEED IP Law Group, LLC
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; A61K38/00 ; A61K39/00 ; A61K48/00 ; C07K14/11 ; C07K14/47 ; C07K14/705 ; C07K16/30 ; C12N9/64 ; C07K14/00 ; C07H21/02 ; C12Q1/68 ; C12N1/20
摘要：
Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
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