发明授权
US06949381B2 Immortalized human skin cell lines and novel serum-free medium useful for the production thereof
失效
永生化人皮肤细胞系和可用于其生产的新型无血清培养基
- 专利标题： Immortalized human skin cell lines and novel serum-free medium useful for the production thereof
- 专利标题（中）： 永生化人皮肤细胞系和可用于其生产的新型无血清培养基
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申请号： US09982649申请日： 2001-10-18
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公开(公告)号： US06949381B2公开(公告)日： 2005-09-27
- 发明人: Markus Baur , Catherine Mace , Armand Malnoe , Andrea M. A. Pfeifer , Marcelle Regnier
- 申请人： Markus Baur , Catherine Mace , Armand Malnoe , Andrea M. A. Pfeifer , Marcelle Regnier
- 申请人地址： CH Vevey
- 专利权人： Nestec S.A.
- 当前专利权人： Nestec S.A.
- 当前专利权人地址： CH Vevey
- 代理机构： Winston & Strawn LLP
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K35/12 ; A61K35/36 ; C12N5/00 ; C12N5/071 ; C12N5/10 ; C12N5/22
摘要：
The present invention relates to improved continuous (immortalized) cell lines, in particular keratinocytes and melanocytes derived from normal human skin tissue. The present invention also relates to novel serum-free media for isolating, producing and maintaining said improved continuous keratinocyte and melanocyte cell lines. The present invention also relates to methods for producing primary melanocytes and keratinocytes under serum-free conditions without any feeder cells.