- 专利标题： Compounds and methods for immunotherapy and diagnosis of tuberculosis
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申请号： US10084843申请日： 2002-02-25
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公开(公告)号： US06962710B2公开(公告)日： 2005-11-08
- 发明人: Steven G. Reed , Yasir A. W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
- 申请人： Steven G. Reed , Yasir A. W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
- 申请人地址： US WA Seattle
- 专利权人： Corixa Corporation
- 当前专利权人： Corixa Corporation
- 当前专利权人地址： US WA Seattle
- 代理机构： Townsend and Townsend and Crew LLP
- 优先权： WOPCT/US96/14674 19960830
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K31/711 ; A61K38/00 ; A61K39/00 ; A61K39/04 ; A61K49/00 ; A61P31/04 ; A61P31/06 ; A61P37/04 ; C07K1/00 ; C07K14/35 ; C12N15/00 ; A61K39/385 ; C07H21/04 ; C12N1/12
摘要：
Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
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