Invention Grant
- Patent Title: Substituted pyrazine derivatives
- Patent Title (中): 取代的吡嗪衍生物
-
Application No.: US10417867Application Date: 2003-04-17
-
Publication No.: US06964965B2Publication Date: 2005-11-15
- Inventor: Jeffrey W. Corbett , Michael Dalton Ennis , Kristine E. Frank , Jian-Min Fu , Robert Louis Hoffman , Patrick R. Verhoest
- Applicant: Jeffrey W. Corbett , Michael Dalton Ennis , Kristine E. Frank , Jian-Min Fu , Robert Louis Hoffman , Patrick R. Verhoest
- Applicant Address: US MI Kalamazoo
- Assignee: Pharmacia & Upjohn
- Current Assignee: Pharmacia & Upjohn
- Current Assignee Address: US MI Kalamazoo
- Agent Peter C. Richardson; Lorrain B. Ling; Andrea E. Dorigo
- Main IPC: G01N33/50
- IPC: G01N33/50 ; A61K31/4965 ; A61K31/497 ; A61P1/00 ; A61P1/14 ; A61P3/04 ; A61P3/08 ; A61P5/00 ; A61P7/12 ; A61P9/00 ; A61P11/06 ; A61P15/08 ; A61P17/00 ; A61P17/06 ; A61P17/14 ; A61P21/00 ; A61P25/00 ; A61P25/04 ; A61P25/06 ; A61P25/08 ; A61P25/20 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P25/32 ; A61P25/34 ; A61P25/36 ; A61P29/00 ; A61P31/18 ; A61P35/00 ; A61P37/06 ; A61P37/08 ; A61P43/00 ; C07D241/20 ; C07D403/12 ; C12Q1/02 ; G01N33/15 ; C07D401/00 ; C07D403/00 ; C07D405/00
Abstract:
The present invention provides substituted pyrazine derivatives of Formula I, that are CRF1 receptor antagonists, including human CRF1 receptors. This invention also relates to use of compounds of the invention for treating a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders, particularly anxiety-related disorders and mood disorders.
Public/Granted literature
- US20040053941A1 Substituted pyrazine derivatives Public/Granted day:2004-03-18
Information query
IPC分类:
