发明授权
- 专利标题： Death domain proteins
- 专利标题（中）： 死亡域蛋白
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申请号： US10001254申请日： 2001-11-15
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公开(公告)号： US06965023B2公开(公告)日： 2005-11-15
- 发明人: John C. Reed , Adam Godzik , Krzysztof Pawlowski , Loredana Fiorentino , Sug Hyung Lee , Wilfried Roth , Frank Stenner-Liewen
- 申请人： John C. Reed , Adam Godzik , Krzysztof Pawlowski , Loredana Fiorentino , Sug Hyung Lee , Wilfried Roth , Frank Stenner-Liewen
- 申请人地址： US CA La Jolla
- 专利权人： The Burnham Institute
- 当前专利权人： The Burnham Institute
- 当前专利权人地址： US CA La Jolla
- 代理机构： McDermott Will & Emery LLP
- 主分类号： C07K14/295
- IPC分类号： C07K14/295 ; C07K14/47 ; C07H21/02 ; C12N5/00 ; C12N15/00 ; C12P21/06
摘要：
In accordance with the present invention, there are provided novel Death Domain (DD), Death Effector Domain (DED) and NB-ARC domain proteins. The invention also provides nucleic acid molecules encoding DD, DED and NB-ARC domain proteins, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention DDs, DEDs or NB-ARC domains. Such DDs, DEDs and NB-ARC domains and/or anti-DD, anti-DED or anti-NB-ARC domain antibodies are useful for discovery of drugs that suppress infection, autoimmunity, inflammation, allergy, allograft rejection, sepsis, and other diseases.
公开/授权文献
- US20030049702A1 Novel death domain proteins 公开/授权日：2003-03-13
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