发明授权
- 专利标题: Neuroprotective agents
- 专利标题(中): 神经保护剂
-
申请号: US10719599申请日: 2003-11-20
-
公开(公告)号: US07026297B2公开(公告)日: 2006-04-11
- 发明人: Lars Eric Sundstrom , Fausto Iannotti , Mark Bradley , Ashley Ker Pringle
- 申请人: Lars Eric Sundstrom , Fausto Iannotti , Mark Bradley , Ashley Ker Pringle
- 申请人地址: GB Hampshire
- 专利权人: University of Southampton
- 当前专利权人: University of Southampton
- 当前专利权人地址: GB Hampshire
- 代理机构: Price, Heneveld, Cooper, DeWitt & Litton, LLP
- 优先权: GB9726569 19971216
- 主分类号: C07K5/06
- IPC分类号: C07K5/06
摘要:
Compounds of formula (I) wherein: Q represents an amidino group, a cyano group or a group of formula XYN—, (where X and Y are hydrogen or various groups); Ra represents alkylene; Rb and Rc each represents alkylene, the total number of carbon atoms in said straight chains of Rb and Rc being 7); R2 and R3 each represents hydrogen, or a group of formula R, RCO—, ROCO—, or RNHCO—, where R represents alkyl or aryl; the chiral carbon atom indicated by the asterisk is in the L configuration; Z is an aromatic amino acid residue; n is 0 or 1; R1 represents hydrogen, alkyl or aryl; and W represents hydrogen, alkyl or aryl; and pharmaceutically acceptable salts thereof have the ability to protect against the neuronal damage which may be caused by an ischemic event.
公开/授权文献
- US20040106560A1 Neuroprotective agents 公开/授权日:2004-06-03
信息查询