- 专利标题： 32142, 21481, 25964, 21686, novel dehydrogenase molecules and uses therefor
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申请号： US10664506申请日： 2003-09-17
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公开(公告)号： US07045325B2公开(公告)日： 2006-05-16
- 发明人: Rachel Meyers , William James Cook , Mark Williamson , Laura A. Rudolph-Owen , Ruth Gimeno
- 申请人： Rachel Meyers , William James Cook , Mark Williamson , Laura A. Rudolph-Owen , Ruth Gimeno
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Wood, Phillips, Katz, Clark & Mortimer
- 主分类号： C12N9/04
- IPC分类号： C12N9/04 ; C12N1/20 ; C12N15/00 ; C12P21/04 ; C07H21/04
摘要：
The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
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