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    21481, a novel dehydrogenase molecule and uses therefor
    3.
    发明授权
    21481, a novel dehydrogenase molecule and uses therefor 有权
    21481，一种新的脱氢酶分子并用于此

    公开(公告)号：US06627423B2

    公开(公告)日：2003-09-30

    申请号：US09838561

    申请日：2001-04-18

    申请人： Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen ,  Ruth Gimeno

    发明人： Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen ,  Ruth Gimeno

    IPC分类号： C12N904

    CPC分类号： C12N9/0004 ,  C07K2319/00 ,  C12N9/0006

    摘要： The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新型DHDR相关脱氢酶分子的分离的核酸分子，命名为DHDR核酸分子。 本发明还提供了反义核酸分子，含有DHDR核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及DHDR基因导入或破坏的非人类转基因动物。 本发明还进一步提供了分离的DHDR蛋白，融合蛋白，抗原肽和抗DHDR抗体。 还提供了利用本发明组合物的诊断方法。

    32142, 21481, 25964, 21686, novel human dehydrogenase molecules and uses therefor
    4.
    发明授权
    32142, 21481, 25964, 21686, novel human dehydrogenase molecules and uses therefor 有权
    32142,21481,25964,21686，新型人脱氢酶分子及其用途

    公开(公告)号：US06613555B2

    公开(公告)日：2003-09-02

    申请号：US09816760

    申请日：2001-03-23

    申请人： Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen

    发明人： Rachel Meyers ,  William James Cook ,  Mark Williamson ,  Laura A. Rudolph-Owen

    IPC分类号： C12N904

    CPC分类号： C12N9/0004 ,  C07K2319/00

    摘要： The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新型DHDR相关脱氢酶分子的分离的核酸分子，命名为DHDR核酸分子。 本发明还提供了反义核酸分子，含有DHDR核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及DHDR基因导入或破坏的非人类转基因动物。 本发明还进一步提供了分离的DHDR蛋白，融合蛋白，抗原肽和抗DHDR抗体。 还提供了利用本发明组合物的诊断方法。