- 专利标题： Methods and reagents for tissue engineering of cartilage in vitro
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申请号： US09844257申请日： 2001-04-27
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公开(公告)号： US07052514B2公开(公告)日： 2006-05-30
- 发明人: Karin Kellner , Kurt Lang , Apollon Papadimitriou , Ulrike Leser-Reiff , Michaela Schultz , Torsten Blunk , Achim Goepferich
- 申请人： Karin Kellner , Kurt Lang , Apollon Papadimitriou , Ulrike Leser-Reiff , Michaela Schultz , Torsten Blunk , Achim Goepferich
- 申请人地址： US MA Cambridge
- 专利权人： Curis, Inc.
- 当前专利权人： Curis, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Fish & Neave IP Group Ropes & Gray LLP
- 主分类号： A61F3/00
- IPC分类号： A61F3/00 ; A61F5/00 ; G01N33/567
摘要：
The present invention makes available an optimal concentration of a hedgehog polypeptide for modulating growth and/or cartilage production by chondrocytes. The present invention allows for improvements in the culturing of chondrocytes to develop cartilaginous tissue ex vivo suitable for implantation to replace damaged or deteriorated cartilage in a patient.
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