发明授权
US07259002B2 Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof
有权
编码新型酰基辅酶A，单酰基甘油酰基转移酶-3（MGAT3）的多核苷酸及其用途
- 专利标题： Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof
- 专利标题（中）： 编码新型酰基辅酶A，单酰基甘油酰基转移酶-3（MGAT3）的多核苷酸及其用途
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申请号： US10761905申请日： 2004-01-21
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公开(公告)号： US07259002B2公开(公告)日： 2007-08-21
- 发明人: John N. Feder , Thomas C. Nelson , Jian Chen , Rupalie Meegalla , Michael Ramaker , Dong Cheng
- 申请人： John N. Feder , Thomas C. Nelson , Jian Chen , Rupalie Meegalla , Michael Ramaker , Dong Cheng
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Brian C. Carey
- 主分类号： C12N9/10
- IPC分类号： C12N9/10 ; C12N1/20 ; C12N15/00 ; C07H21/04
摘要：
The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing MGAT3 polypeptides, fragments, and homologues thereof. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
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