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15 条记录 (耗时 0.062 秒)

    Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof
    3.
    发明授权
    Polynucleotide encoding a novel acyl coenzyme A, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof 有权
    编码新型酰基辅酶A，单酰基甘油酰基转移酶-3（MGAT3）的多核苷酸及其用途

    公开(公告)号：US07259002B2

    公开(公告)日：2007-08-21

    申请号：US10761905

    申请日：2004-01-21

    申请人： John N. Feder ,  Thomas C. Nelson ,  Jian Chen ,  Rupalie Meegalla ,  Michael Ramaker ,  Dong Cheng

    发明人： John N. Feder ,  Thomas C. Nelson ,  Jian Chen ,  Rupalie Meegalla ,  Michael Ramaker ,  Dong Cheng

    IPC分类号： C12N9/10 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

    CPC分类号： C12N9/1029

    摘要： The present invention provides novel polynucleotides encoding MGAT3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing MGAT3 polypeptides, fragments, and homologues thereof. The invention further relates to diagnostic and therapeutic methods for applying these novel MGAT3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, such as obesity. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码MGAT3多肽的新型多核苷酸，其片段及其同源物。 还提供载体，宿主细胞，抗体，以及用于产生MGAT3多肽，其片段及其同源物的重组和合成方法。 本发明还涉及将这些新型MGAT3多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症如肥胖症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Testis-specific tubulin tyrosine-ligase-like protein, BGS42
    4.
    发明授权
    Testis-specific tubulin tyrosine-ligase-like protein, BGS42 有权
    睾丸特异性微管蛋白酪氨酸连接酶样蛋白BGS42

    公开(公告)号：US07122358B2

    公开(公告)日：2006-10-17

    申请号：US10635977

    申请日：2003-08-07

    申请人： John N. Feder ,  Thomas C. Nelson ,  Shujian Wu

    发明人： John N. Feder ,  Thomas C. Nelson ,  Shujian Wu

    IPC分类号： C12N9/00 ,  C12N1/20 ,  C12N15/00 ,  C07K1/00

    CPC分类号： C12N9/93 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  C07K2319/00

    摘要： The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-42多肽的新型多核苷酸，其片段和同源物。还提供了用于产生所述多肽的载体，宿主细胞，抗体以及重组和合成方法。 本发明还涉及将这些新型BGS-42多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Data stream independent printer
    5.
    发明授权
    Data stream independent printer 失效

    公开(公告)号：US5025398A

    公开(公告)日：1991-06-18

    申请号：US526505

    申请日：1990-05-21

    申请人： Thomas C. Nelson

    发明人： Thomas C. Nelson

    IPC分类号： G06F3/12 ,  G06K15/00

    CPC分类号： G06K15/00

    摘要： The above described problems are solved and a technical advance achieved in the field by the data stream independent printer of the present invention. This printer is a nonimpact printer that is compatible with host processors that are programmed to operate line printers and host processors that are programmed to operate nonimpact printers. This compatibility is achieved by the use of conversion apparatus that emulates the operation of a line printer, such as a high speed band printer, when the associated host processor is programmed to operate high speed line printers. The conversion apparatus responds to the line printer control signals produced by the host processor to control the operation of the nonimpact printer. This conversion apparatus stores a plurality of character set definitions, overlays, copy modifications and setups on a disk drive memory located in the printer system so that the band definition information provided by the host can be translated into print character generation control signals. In operation, the host processor transmits a band identification data to the printer system, which data is used to retrieve from the disk memory to form and format of the character set that is available to the host processor. The host processor then transmits lines of printing into a line buffer located in the conversion apparatus. The lines of printing are formatted by the host processor as data indicative of a selected character on the print band and its desired position in the line of output print. The conversion apparatus translates the character identification and position into control signals that cause the nonimpact printer to generate the requested character in the requested position on a page basis with any named overlays and copy modifications. The use of this conversion apparatus enables nonimpact printers to be substituted for high speed line printers without any corresponding reprogramming of the software on the front processor. The conversion apparatus emulates the operation of a high speed line printer to the host processor while simultaneously emulating a nonimpact printer programmed host processor to the nonimpact printer.

    Method of diagnosing lung cancer using BGS42
    6.
    发明授权
    Method of diagnosing lung cancer using BGS42 有权
    使用BGS42诊断肺癌的方法

    公开(公告)号：US07741025B2

    公开(公告)日：2010-06-22

    申请号：US11900344

    申请日：2007-09-10

    申请人： John N. Feder ,  Shujian Wu ,  Thomas C. Nelson ,  Liana M. Lee

    发明人： John N. Feder ,  Shujian Wu ,  Thomas C. Nelson ,  Liana M. Lee

    IPC分类号： C12Q1/70 ,  C12Q1/68

    CPC分类号： C12N9/93 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  C07K2319/00 ,  G01N33/57423 ,  G01N2333/9015 ,  Y10S435/81

    摘要： The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-42多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-42多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Polynucleotides encoding a novel metalloprotease, MP-1
    8.
    发明授权
    Polynucleotides encoding a novel metalloprotease, MP-1 有权
    编码新型金属蛋白酶MP-1的多核苷酸

    公开(公告)号：US06642041B2

    公开(公告)日：2003-11-04

    申请号：US10067443

    申请日：2002-02-05

    申请人： Jian Chen ,  John N. Feder ,  Thomas C. Nelson ,  Stanley R. Krystek ,  Franck Duclos

    发明人： Jian Chen ,  John N. Feder ,  Thomas C. Nelson ,  Stanley R. Krystek ,  Franck Duclos

    IPC分类号： C12N948

    CPC分类号： C12N9/6489 ,  C07K2299/00

    摘要： The present invention provides novel polynucleotides encoding MP-1 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MP-1 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码MP-1多肽，其片段和同系物的新型多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型MP-1多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Printer switchable between duplex and simplex mode on a page by page basis
    9.
    发明授权
    Printer switchable between duplex and simplex mode on a page by page basis 失效
    打印机可以在双面和单面模式之间逐页切换

    公开(公告)号：US4924275A

    公开(公告)日：1990-05-08

    申请号：US351429

    申请日：1989-05-12

    申请人： Thomas C. Nelson

    发明人： Thomas C. Nelson

    IPC分类号： B41J3/60 ,  G03G15/23

    CPC分类号： B41J3/60 ,  G03G15/234

    摘要： The printer switchable between simplex and duplex mode of operation on a page by page basis makes use of a single simplex print engine. Duplex printing is accomplished by the reinsertion of a simplex printed page into the input of the print engine in a flipped mode so the other side of the printed page can be printed by the print engine. This printer also includes apparatus that dynamically switches the operation of the printer from duplex to simplex mode of operation when the printing commands input from the associated processor indicates that the other side of a simplex printed page is a blank page. This enables the print engine to eject the simplex printed page directly to the output paper bin without having to cycle this simplex printed page back through the print engine even though there are no characters to be printed thereon. This blank page suppression or simplex/duplex mode switching thereby increases the throughput of this printer system by avoiding the unnecessary delays occasioned by cycling a page of paper through the print engine when nothing is to printed thereon.

    摘要翻译： 可以在单页和双工操作模式之间逐页切换的打印机使用单个单面打印引擎。 双面打印是通过将单面打印页面以翻转模式重新插入打印引擎的输入来实现的，因此打印页面的另一面可以由打印引擎打印。 该打印机还包括当从相关联的处理器输入的打印命令指示单面打印页面的另一侧是空白页时，将打印机的操作从双工模式动态地切换到单工模式的装置。 这使得打印机能够将单面打印页面直接排出到输出纸盒，而不必将该单面打印页面循环通过打印引擎，即使没有要打印的字符。 这种空白页面抑制或单面/双面模式切换从而通过避免当没有打印在其上时通过打印引擎循环打印一页纸而引起的不必要的延迟来增加该打印机系统的吞吐量。