发明授权
- 专利标题: Nucleotide analogs with six-membered rings
- 专利标题(中): 具有六元环的核苷酸类似物
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申请号: US10816298申请日: 2004-04-01
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公开(公告)号: US07276592B2公开(公告)日: 2007-10-02
- 发明人: Frank Bergmann , Horst Donner , Herbert Von Der Eltz , Dieter Heindl , Piet Herdewijn
- 申请人: Frank Bergmann , Horst Donner , Herbert Von Der Eltz , Dieter Heindl , Piet Herdewijn
- 申请人地址: US IN Indianapolis
- 专利权人: Roche Diagnostics Operations, Inc.
- 当前专利权人: Roche Diagnostics Operations, Inc.
- 当前专利权人地址: US IN Indianapolis
- 代理商 Marilyn L. Amick
- 优先权: EP03007844 20030405
- 主分类号: C07G3/00
- IPC分类号: C07G3/00 ; C07H21/00 ; C07H19/04 ; C12Q1/68
摘要:
The present invention is related to compounds comprising six-membered rings capable of being incorporated into nucleic acids. Particularly, the six-membered ring is a derivative of cyclohexane, cyclohexene, tetrahydropyran, tetrahydrothiopyran or piperidine. These compounds may be used to build up oligomeric compounds. The invention is further related to uses of these oligomeric compounds for hybridization and as probes. In addition, methods for the detection of nucleic acids are provided wherein the oligomeric compounds are used.
公开/授权文献
- US20050004078A1 Nucleotide analogs with six-membered rings 公开/授权日:2005-01-06
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