发明授权
- 专利标题： Diazepan derivatives or salts thereof
- 专利标题（中）： 二氮杂环庚烷衍生物或其盐
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申请号： US10656129申请日： 2003-09-08
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公开(公告)号： US07307074B2公开(公告)日： 2007-12-11
- 发明人: Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
- 申请人： Fukushi Hirayama , Hiroyuki Koshio , Tsukasa Ishihara , Norio Seki , Shunichiro Hachiya , Keizo Sugasawa , Ryota Shiraki , Yuji Koga , Yuzo Matsumoto , Takeshi Shigenaga , Souichirou Kawazoe
- 申请人地址： JP Tokyo
- 专利权人： Astellas Pharma Inc.
- 当前专利权人： Astellas Pharma Inc.
- 当前专利权人地址： JP Tokyo
- 代理机构： Fitzpatrick, Cella, Harper & Scinto
- 优先权： JP2000-096858 20000331
- 主分类号： A61P7/02
- IPC分类号： A61P7/02 ; A61K31/55 ; C07D223/04 ; C07D401/00
摘要：
To provide a compound which has an anticoagulation action based upon inhibition of activated blood coagulation factor X and is useful as an anticoagulant or an agent for prevention and treatment of diseases caused by thrombus or embolus. A diazepan derivative such as 4-[(3-carbamimidoylphenylamino)methyl]-3-[4-(4-methyl-1,4-diazepan-1-yl)benzoylamino]benzoic acid and 3-hydroxy-4′-methoxy-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzanilide or a salt thereof is an effective ingredient.
公开/授权文献
- US20040068109A1 Diazepan derivatives or salts thereof 公开/授权日：2004-04-08
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