发明授权
- 专利标题: Oxindole derivatives
- 专利标题(中): 羟吲哚衍生物
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申请号: US11471363申请日: 2006-06-20
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公开(公告)号: US07576082B2公开(公告)日: 2009-08-18
- 发明人: Kin-Chun Luk , Sung-Sau So , Jing Zhang , Zhuming Zhang
- 申请人: Kin-Chun Luk , Sung-Sau So , Jing Zhang , Zhuming Zhang
- 申请人地址: US NJ Nutley
- 专利权人: Hoffman-La Roche Inc.
- 当前专利权人: Hoffman-La Roche Inc.
- 当前专利权人地址: US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni
- 主分类号: A61K31/535
- IPC分类号: A61K31/535 ; A61K31/445 ; A61K31/415 ; A61K31/40 ; C07D413/00 ; C07D401/00 ; C07D403/02 ; C07D487/00 ; C07D209/04
摘要:
The invention describes compounds of the general formula I or the pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and X are herein described, a process for their manufacture, medicaments containing them as well as the use of these compounds as pharmaceutically active agents. The compounds show activity as antiproliferative agents and may be especially useful for the treatment of cancer.
公开/授权文献
- US20060293319A1 Oxindole derivatives 公开/授权日:2006-12-28
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