发明授权
- 专利标题： Anti-hepatitis a virus antibodies
- 专利标题（中）： 抗乙型肝炎病毒抗体
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申请号： US11789377申请日： 2007-04-23
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公开(公告)号： US07635476B2公开(公告)日： 2009-12-22
- 发明人: Darren J. Schofield , Suzanne U. Emerson , Robert Purcell, II
- 申请人： Darren J. Schofield , Suzanne U. Emerson , Robert Purcell, II
- 申请人地址： US DC Washington
- 专利权人： The United States of America as represented by the Secretary of the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Secretary of the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Klarquist Sparkman, LLP
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C12N15/00 ; C12P21/06 ; G01N33/53
摘要：
Chimpanzee monoclonal antibodies and antigen binding fragments including a γ1-chain CDR3 region that bind hepatitis A virus (HAV) antigen are disclosed herein. The antibodies neutralize HAV. Also disclosed are methods for using these antibodies and antigen binding fragments in the detection of hepatitis A virus, the inhibition of infection of a subject with hepatitis A virus, and in screening for agents that affect HAV.
公开/授权文献
- US20070287667A1 Anti-hepatitis a virus antibodies 公开/授权日：2007-12-13
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