Invention Grant
- Patent Title: Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
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Application No.: US12353237Application Date: 2009-01-13
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Publication No.: US08263747B2Publication Date: 2012-09-11
- Inventor: James D. Marks , Peter Amersdorfer , Ali Razai
- Applicant: James D. Marks , Peter Amersdorfer , Ali Razai
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis, LLP
- Agent Carol L. Francis
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K39/395 ; A61K39/40 ; A61K39/42 ; A01N37/18 ; C07K16/00 ; C12P21/08 ; G01N33/00
Abstract:
This invention provides antibodies that specifically bind to and neutralize botulinum neurotoxin type A (BoNT/A) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
Public/Granted literature
- US20090123481A1 THERAPEUTIC MONOCLONAL ANTIBODIES THAT NEUTRALIZE BOTULINUM NEUROTOXINS Public/Granted day:2009-05-14
Information query
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