Invention Grant
- Patent Title: 7-substituted indole MCL-1 inhibitors
- Patent Title (中): 7-取代吲哚MCL-1抑制剂
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Application No.: US12104294Application Date: 2008-04-16
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Publication No.: US08445679B2Publication Date: 2013-05-21
- Inventor: Xilu Wang , Xiaohong Song , Steven W. Elmore , Milan Bruncko , David J. Madar , Andrew J. Souers , Lisa A. Hasvold , Le Wang , Zhi-Fu Tao , Aaron K. Kunzer
- Applicant: Xilu Wang , Xiaohong Song , Steven W. Elmore , Milan Bruncko , David J. Madar , Andrew J. Souers , Lisa A. Hasvold , Le Wang , Zhi-Fu Tao , Aaron K. Kunzer
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Jones Day
- Main IPC: C07D403/04
- IPC: C07D403/04 ; A61K31/497
Abstract:
Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds, and methods of treating diseases involving overexpressed or unregulated Mcl-1 protein are disclosed.
Public/Granted literature
- US20090054402A1 7-SUBSTITUTED INDOLE MCL-1 INHIBITORS Public/Granted day:2009-02-26
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