发明授权
US08604169B2 Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
有权
称为251P5G2的核酸和相应的蛋白质可用于治疗和检测癌症
- 专利标题： Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
- 专利标题（中）： 称为251P5G2的核酸和相应的蛋白质可用于治疗和检测癌症
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申请号： US12651336申请日： 2009-12-31
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公开(公告)号： US08604169B2公开(公告)日： 2013-12-10
- 发明人: Arthur B. Raitano , Pia M. Challita-Eid , Aya Jakobovits , Mary Faris , Wangmao Ge
- 申请人： Arthur B. Raitano , Pia M. Challita-Eid , Aya Jakobovits , Mary Faris , Wangmao Ge
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; C12P21/08 ; G01N33/53 ; A61K39/395 ; A61K39/21
摘要：
A novel gene 251P5G2 and its encoded protein, and variants thereof, are described wherein 251P5G2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 251P5G2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 251P5G2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 251P5G2 can be used in active or passive immunization.
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