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US08697654B2 Peptide linkers for effective multivalent peptide binding 失效
用于有效多价肽结合的肽接头

Peptide linkers for effective multivalent peptide binding
摘要:
Short single chain peptides having affinity for a target surface often lack the binding durability required for certain commercial applications. One way to improve durability is to promote multivalent binding by linking together binding sequences using peptide linkers. However, the resulting single chain binding peptides often suffer from linker entropy. It has been discovered that the use of rigid peptide linkers when linking together multiple binding sequences enhances the binding affinity of the resulting single chain peptide.
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