发明授权
- 专利标题: Wound healing profile
- 专利标题(中): 伤口愈合情况
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申请号: US10589150申请日: 2005-02-14
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公开(公告)号: US08765169B2公开(公告)日: 2014-07-01
- 发明人: Paul Kemp , Györgyi Talas , Jennifer Sutherland , Margaret Batten , Penelope Ann Johnson , Andrew Shering , Michael McWhan
- 申请人: Paul Kemp , Györgyi Talas , Jennifer Sutherland , Margaret Batten , Penelope Ann Johnson , Andrew Shering , Michael McWhan
- 申请人地址: US TN Memphis
- 专利权人: Smith & Nephew, Inc.
- 当前专利权人: Smith & Nephew, Inc.
- 当前专利权人地址: US TN Memphis
- 代理机构: Fulbright & Jaworski LLP
- 优先权: GB0403220.7 20040213; GB0403226.4 20040213; GB0426252.3 20041130
- 国际申请: PCT/GB2005/000511 WO 20050214
- 国际公布: WO2005/079821 WO 20050901
- 主分类号: A61F13/00
- IPC分类号: A61F13/00 ; A61K9/70 ; C12N5/071 ; C12N5/00 ; C12N5/02
摘要:
The present invention relates to compositions and methods for tissue regeneration, particularly for treating skin lesions such as wounds. In one aspect, the invention provides wound healing composition characterized by the higher expression levels of phenotypic marker genes such as apolipoprotein D, matrix metalloprotease (2), collagen 3a1 and smooth muscle actin than the housekeeping gene ribosomal protein L32. The compositions and methods of the invention are useful especially for assisting the process of wound healing, particularly chronic open lesions that are slow to heal or resistant to healing.
公开/授权文献
- US20080193507A1 Wound Healing Profile 公开/授权日:2008-08-14
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