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US08765436B2 DNA polymerases with increased 3′-mismatch discrimination 有权
具有增加的3'-不匹配鉴别的DNA聚合酶

DNA polymerases with increased 3′-mismatch discrimination
摘要:
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
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