Invention Grant
- Patent Title: Genetically encoded photomanipulation of protein and peptide activity
- Patent Title (中): 遗传编码的蛋白质和肽活性的光调制
-
Application No.: US13381383Application Date: 2010-07-01
-
Publication No.: US08859232B2Publication Date: 2014-10-14
- Inventor: Klaus Hahn , Yi Wu , Brian Kuhlman
- Applicant: Klaus Hahn , Yi Wu , Brian Kuhlman
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- International Application: PCT/US2010/040747 WO 20100701
- International Announcement: WO2011/002977 WO 20110106
- Main IPC: C12P21/04
- IPC: C12P21/04 ; C12N1/20 ; C12N1/15 ; C12N15/00 ; C07H21/04 ; G01N33/542 ; C12N9/16
Abstract:
The present invention relates to fusion proteins comprising protein light switches and methods of photomanipulating the activity of the proteins. The invention further relates to polynucleotides and vectors encoding the fusion proteins, cells comprising the fusion proteins, and methods of using the fusion proteins to study protein function and analyze subcellular activity, as well as diagnostic and therapeutic methods.
Public/Granted literature
- US20120165204A1 Genetically Encoded Photomanipulation of Protein and Peptide Activity Public/Granted day:2012-06-28
Information query
