Invention Grant
- Patent Title: 3-amino-pyridines as GPBAR1 agonists
- Patent Title (中): 3-氨基 - 吡啶类作为GPBAR1激动剂
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Application No.: US13406572Application Date: 2012-02-28
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Publication No.: US08987307B2Publication Date: 2015-03-24
- Inventor: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Prabha Saba Karnachi , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
- Applicant: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Prabha Saba Karnachi , Kyungjin Kim , Rainer E. Martin , Patrizio Mattei , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ullmer
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Priority: EP11156711 20110303
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D213/72 ; C07D213/75 ; C07D213/81 ; C07D213/82 ; C07D401/04 ; C07D401/12 ; C07D401/14 ; C07D405/04 ; C07D405/12 ; C07D413/04 ; C07D413/12 ; C07D417/04 ; C07D417/12 ; C07D491/107
Abstract:
This invention relates to novel 3-aminopyridines of the formula wherein B1, B2 and R1 to R6 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
Public/Granted literature
- US20120232051A1 3-AMINO-PYRIDINES AS GPBAR1 AGONISTS Public/Granted day:2012-09-13
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